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Image Search Results


The result of three Hadamard time-encoded, background suppressed pCASL-scans of 5.5 min each (scans acquired on a 3 T MRI scanner (Ingenia, Philips, The Netherlands) on a 43-year-old volunteer who provided informed consent under an approved IRB-protocol; scanner software was locally adapted to allow time-encoded ASL); all sub-boli images have been corrected for T1-decay of label based upon a T1 of 1650 ms. (a) Hadamard-8 matrix with seven blocks of 500 ms each with an additional 500 ms delay before start of the readout module. (b) Hadamard-8 ‘free lunch’ matrix with a perfusion block of 2000 ms and six blocks of 250 ms each with an additional 500 ms delay before start of readout. (c) Hadamard-8 ‘T1-compensated’ matrix with seven blocks of respectively 1175, 683, 482, 374, 305, 257 and 224 ms with an additional 500 ms delay before start of readout. Block duration selected based upon T1-compensation with a T1 of 1650 ms. (d) Result of summing sub-boli 1–4 from the equidistant (traditional) Hadamard-8 matrix (a). (e) The first sub-bolus image of the free lunch approach (b) for comparison purposes.

Journal: Journal of Cerebral Blood Flow & Metabolism

Article Title: Advances in arterial spin labelling MRI methods for measuring perfusion and collateral flow

doi: 10.1177/0271678X17713434

Figure Lengend Snippet: The result of three Hadamard time-encoded, background suppressed pCASL-scans of 5.5 min each (scans acquired on a 3 T MRI scanner (Ingenia, Philips, The Netherlands) on a 43-year-old volunteer who provided informed consent under an approved IRB-protocol; scanner software was locally adapted to allow time-encoded ASL); all sub-boli images have been corrected for T1-decay of label based upon a T1 of 1650 ms. (a) Hadamard-8 matrix with seven blocks of 500 ms each with an additional 500 ms delay before start of the readout module. (b) Hadamard-8 ‘free lunch’ matrix with a perfusion block of 2000 ms and six blocks of 250 ms each with an additional 500 ms delay before start of readout. (c) Hadamard-8 ‘T1-compensated’ matrix with seven blocks of respectively 1175, 683, 482, 374, 305, 257 and 224 ms with an additional 500 ms delay before start of readout. Block duration selected based upon T1-compensation with a T1 of 1650 ms. (d) Result of summing sub-boli 1–4 from the equidistant (traditional) Hadamard-8 matrix (a). (e) The first sub-bolus image of the free lunch approach (b) for comparison purposes.

Article Snippet: The result of three Hadamard time-encoded, background suppressed pCASL-scans of 5.5 min each (scans acquired on a 3 T MRI scanner (Ingenia, Philips, The Netherlands) on a 43-year-old volunteer who provided informed consent under an approved IRB-protocol; scanner software was locally adapted to allow time-encoded ASL); all sub-boli images have been corrected for T1-decay of label based upon a T1 of 1650 ms. (a) Hadamard-8 matrix with seven blocks of 500 ms each with an additional 500 ms delay before start of the readout module. (b) Hadamard-8 ‘free lunch’ matrix with a perfusion block of 2000 ms and six blocks of 250 ms each with an additional 500 ms delay before start of readout. (c) Hadamard-8 ‘T1-compensated’ matrix with seven blocks of respectively 1175, 683, 482, 374, 305, 257 and 224 ms with an additional 500 ms delay before start of readout.

Techniques: Software, Blocking Assay, Comparison

Example of the potential of multiband (also known as simultaneous multi-slice (SMS) acquisition) for ASL (scans acquired on a 3 T MRI scanner (Ingenia, Philips, The Netherlands; scanner software was locally adapted to allow multiband ASL) on a 43-year-old, male volunteer who provided informed consent under an approved IRB-protocol for protocol development). Left: traditional readout with single-shot EPI (half Fourier of 0.8; readout time per slice 60 ms; 24 slices; 1800 ms labelling duration; 1800 ms PLD; two background suppression inversion pulses; 30 averages; total scan time 5m08s). Right: same settings except for multiband factor of 4; 38 averages; total scan time 5m11s. Upper row: coronal reconstruction of mean control scans showing a gradual decrease in background suppression efficiency for the traditional readout (Left) and four bands of decreasing background suppression efficiency for the multiband-4 readout (Right). Middle row: ASL-images. Lower row: SNR images calculated as ASL-signal divided by standard deviation over the acquired averages multiplied by the square root of the number of averages to achieve the effective SNR corrected for the shorter achievable TR for multiband readout as compared to the traditional readout.

Journal: Journal of Cerebral Blood Flow & Metabolism

Article Title: Advances in arterial spin labelling MRI methods for measuring perfusion and collateral flow

doi: 10.1177/0271678X17713434

Figure Lengend Snippet: Example of the potential of multiband (also known as simultaneous multi-slice (SMS) acquisition) for ASL (scans acquired on a 3 T MRI scanner (Ingenia, Philips, The Netherlands; scanner software was locally adapted to allow multiband ASL) on a 43-year-old, male volunteer who provided informed consent under an approved IRB-protocol for protocol development). Left: traditional readout with single-shot EPI (half Fourier of 0.8; readout time per slice 60 ms; 24 slices; 1800 ms labelling duration; 1800 ms PLD; two background suppression inversion pulses; 30 averages; total scan time 5m08s). Right: same settings except for multiband factor of 4; 38 averages; total scan time 5m11s. Upper row: coronal reconstruction of mean control scans showing a gradual decrease in background suppression efficiency for the traditional readout (Left) and four bands of decreasing background suppression efficiency for the multiband-4 readout (Right). Middle row: ASL-images. Lower row: SNR images calculated as ASL-signal divided by standard deviation over the acquired averages multiplied by the square root of the number of averages to achieve the effective SNR corrected for the shorter achievable TR for multiband readout as compared to the traditional readout.

Article Snippet: The result of three Hadamard time-encoded, background suppressed pCASL-scans of 5.5 min each (scans acquired on a 3 T MRI scanner (Ingenia, Philips, The Netherlands) on a 43-year-old volunteer who provided informed consent under an approved IRB-protocol; scanner software was locally adapted to allow time-encoded ASL); all sub-boli images have been corrected for T1-decay of label based upon a T1 of 1650 ms. (a) Hadamard-8 matrix with seven blocks of 500 ms each with an additional 500 ms delay before start of the readout module. (b) Hadamard-8 ‘free lunch’ matrix with a perfusion block of 2000 ms and six blocks of 250 ms each with an additional 500 ms delay before start of readout. (c) Hadamard-8 ‘T1-compensated’ matrix with seven blocks of respectively 1175, 683, 482, 374, 305, 257 and 224 ms with an additional 500 ms delay before start of readout.

Techniques: Software, Control, Standard Deviation